Laser medicine is a technology that utilizes the characteristics of laser for medical diagnosis and treatment. Laser medical treatment has become an important branch of medicine, but also an important branch of laser technology application. Laser medicine is a special use of laser technology to study, diagnose and treat diseases, mainly with different bands of laser and human organs and tissues to achieve the purpose of treatment. From the specific application range of lasers in the medical field, the laser is mainly used in diagnosis, treatment, beauty, life science research, and other fields, and laser medical equipment is the basis for laser medical development.
(2) Photodynamic therapy
PDT is a new minimally invasive treatment for tumors following surgery, chemotherapy, and radiotherapy. In the process of PDT, a series of photo physicochemical reactions occur when the photosensitizer is activated by a specific wavelength laser, which produces biotoxic reactive oxygen species to kill the target tissue and then implement targeted therapy. Compared with traditional treatment methods, PDT has the advantages of high selectivity, minimally invasive, reusable, non-drug resistance, and maximum preservation of tissue and organ integrity. With the deepening of the research on the mechanism of PDT, the indications of PDT have gradually expanded from the initial tumor therapy to three therapeutic fields: tumor targeting PDT, vascular targeting PDT, and microbial targeting PDT. It has a good application prospect in malignant tumors and precancerous lesions, refractory microvascular lesions (such as senile fundus macular degeneration, bright red nevus, antral vascular dilatation, etc.), and refractory/drug-resistant microbial infections.
The treatment spectrum and curative effect of PDT are closely related to the light parameters such as wavelength, intensity, and illumination mode, so the light source is the key component of PDT. In the early application stage, usually use incandescent lamps, high voltage arc lamps and other incoherent light as the radiation source, such light sources in the spectral structure, power density, transmission system, accurate control and so on there are shortcomings. In view of the unique advantages of laser technology, the laser has become the preferred light source for PDT, significantly improving the effect of PDT clinical applications.
The mechanism of action of PDT is unique and complex, with a wide range of therapeutic spectrum and different characteristics of specific therapeutic targets. To carry out systematic and in-depth research on different target diseases to achieve new therapeutic breakthroughs, which is the most active research direction of laser therapy at present, the corresponding hot spots mainly include Research and development of highly targeted and highly selective functional photosensitizers, enhancement of PDT treatment depth (such as two-photon PDT, up-conversion nanomaterials PDT, etc.), research and development and application of new PDT light sources, new indication mechanism and dose-effect research of PDT, precise regulation of light dose in PDT treatment, etc.
(3) Low laser treatment
LLLT, also known as low-intensity laser therapy or photobiological regulation therapy, refers to the laser acting on biological tissues that does not cause irreversible damage, but stimulates the body to produce a series of physiological and biochemical reactions, and plays a regulating, enhancing, or inhibiting effect on the tissues or the body to achieve the purpose of treating diseases. The biggest feature of LLLT is that the patient is non-invasive and painless, and its power density is usually on the order of milliwatts. Since the 1970s, LLLT has been widely used clinically in Eastern Europe, the Soviet Union, and China. With the development of semiconductor lasers, lasers of various wavelengths, including red light and near-infrared light, are used as LLLT treatment light sources for more than 300 diseases in internal medicine, surgery, gynecology, pediatrics, ophthalmology, ear, stomatology, and other clinical departments. It has a good effect on promoting wound healing, pain relief, inflammation subsides, tissue regeneration, muscle fatigue relief, and so on. At present, clinical lasers are mainly HeNe/ semiconductor lasers, with wavelengths in the red band (630~690 nm) and near-infrared band (760~940 nm), mainly using continuous output mode.
The laser wavelength, laser dose, and continuous or pulsed laser output mode will produce different biological regulatory processes. With the in-depth study of the mechanism of LLLT and the emergence and application of new light sources, the application field of LLLT is also constantly expanding, in addition to clinical mature applications (such as infection, inflammation, pain), ultraviolet and near-infrared pulsed laser in some major chronic diseases and age-related diseases in the treatment and prevention of good prospects. In recent years, the exploration of LLLT in the prevention and treatment of neurodegenerative diseases has made some progress. In the absence of any safe and effective method to treat neurodegenerative diseases, LLLT opens up a promising new direction that is expected to drive the clinical application of low-intensity laser and the further development of related laser technologies.
With the change of the medical model and the expansion of the LLLT disease spectrum from common diseases to major chronic age-related diseases, related treatment fields are extending from disease treatment to disease prevention, and the main application battlefield has also changed from medical institutions to communities and families. This situation puts forward new and higher requirements for the portability, miniaturization, and wearability of LLLT treatment equipment. It can be expected that wearable devices based on laser technology will play a more common and important role in the treatment of diseases.
3. Laser monitoring technology
Medical monitoring technology based on light-emitting diode (LED) light sources has gradually emerged because of its ability to monitor important physiological indicators such as blood sugar and blood oxygen. Compared with LED light sources, laser light sources have better optical characteristics and can provide a new non-destructive and accurate monitoring means: to achieve minimally invasive or non-invasive monitoring, with high sensitivity, high selectivity, and long-term stability, significantly improving the accuracy of medical monitoring results. With the transformation of the medical treatment model, the "hospital treatment + family health monitoring" model will be the development trend, and precision laser monitoring technology is becoming an important development direction of medical monitoring equipment.
In terms of highly sensitive laser health monitoring, laser monitoring technology based on breath gas, urine, and blood is the focus of future development.
In terms of miniaturized laser health monitoring, (1) portable laser monitoring technology is developed, and the laser monitoring system is miniaturized and integrated, such as portable blood glucose and blood pressure detector; Develop wearable laser monitoring technology, design laser monitoring equipment suitable for human wear, such as wearable smart laser monitoring watches; (3) The development of endoscopic laser monitoring technology, combining the laser technology that carries out molecular, cellular and tissue level detection with the current mature endoscopic technology for real-time monitoring of tissues in vivo.
In terms of intelligent laser health monitoring, (1)the development of laser monitoring functions based on big data, artificial intelligence technology will become a powerful tool for automated processing and analysis of biomedical big data; (2) According to the needs of dynamic medical testing, the development of small volume, lightweight, low voltage and power consumption of laser light source, improve the physical indicators of diagnostic lasers and equipment endurance to meet the requirements of user experience; (3) The future laser diagnosis and treatment methods are developing in the direction of implantation, and the biocompatibility and degradability of new lasers such as micro-nano lasers are explored.
Contact information:
If you have any ideas, feel free to talk to us. No matter where our customers are and what our requirements are, we will follow our goal to provide our customers with high quality, low prices, and the best service.
Email：info@loshield.com
Tel：0086-18092277517
Fax： 86-29-81323155
Wechat：0086-18092277517
